Isobaric levobupivacaine for intrathecal anesthesia as an effective and safe option in transurethral resection of the prostate surgery

Tjokorda Gde Agung Senapathi, I Made Gede Widnyana, I Ketut Wibawa Nada, Mira Kusuma Astuti

Tjokorda Gde Agung Senapathi
Udayana University

I Made Gede Widnyana
Udayana University

I Ketut Wibawa Nada
Udayana University

Mira Kusuma Astuti
Udayana University. Email:
Online First: August 30, 2019 | Cite this Article
Senapathi, T., Widnyana, I., Nada, I., Astuti, M. 2019. Isobaric levobupivacaine for intrathecal anesthesia as an effective and safe option in transurethral resection of the prostate surgery. Bali Journal of Anesthesiology 3(2). DOI:10.15562/bjoa.v3i2.187

The search for safer anesthetic solutions has always been one of the primary needs in anesthesiology practice. Levobupivacaine, the pure S (-) enantiomer of bupivacaine, emerged as a safer alternative for intrathecal anesthesia than its racemic parent (bupivacaine). Levobupivacaine shows a lower risk of the central nervous system and cardiovascular toxicity.However, in many countries, levobupivacaine is only available in isobaric solution, where the isobaric solution for intrathecal anesthesia is still often be questioned its effectiveness because of the fear that the block spreading is unpredictable. In this case series, we describe sensory and motor block characteristics, hemodynamics profile and adverse effects of isobaric levobupivacaine in intrathecal anesthesia for six patients with American Society of Anesthesiology physical status II-III whose undergo transurethral endoscopic surgery.


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